UNC5C Antilichaam

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) -like domains and 2 type I thrombospondin motifs in the extracellular region.

8633

O95185

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 300-360 of human UNC5C (NP_003719.3) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Neuroscience

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 103kDa

IgG

WB: 1:500 - 1:2000

UNC5C

293T

Mouse brain

Mouse lung

Rat brain

Unc-5 homolog C (C. elegans)

Homo sapiens

Unc5C, unc5 (C.elegans homolog) c, homolog of C. elegans transmembrane receptor Unc5, UNC5H3, unc-5 homolog C (C. elegans), UNC5C

WB

Liquid