UNC8969
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
UNC8969 is a potent and selective macrocyclic dual inhibitor of MERTK and AXL with low nanomolar IC50 values. It demonstrates favorable pharmacokinetics and has shown significant anti-tumor efficacy in cellular models of lung cancer, supporting its utility in oncology research for studying TAM receptor signaling in vitro and in vivo.
3036049-17-6
Signal Transduction
CC1=CC=C (N2) C=C1OC/C=C\CNC3=NC2=C (C (N[C@@H]4CC[C@@H] (C (NCCN (CC) CC) =O) CC4) =O) C=N3
C29H41N7O3
535.68
-20°C
For research use only.
Beschrijving
UNC8969 is a potent and selective macrocyclic dual inhibitor of MERTK and AXL with low nanomolar IC50 values. It demonstrates favorable pharmacokinetics and has
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