UPF3A Antilichaam - middengebied: HRP (ARP41000_P050-HRP)

UPF3 regulator of nonsense transcripts homolog A (yeast)

UPF3, HUPF3A, RENT3A

65110

Q9H1J1

NP_075387

Human

The immunogen is a synthetic peptide directed towards the middle region of human UPF3A

UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon j

HTT; SMG1; HBB; APP; RNPS1; NXF1; SRRM1; TOPORS; PIGT; ALYREF; IFITM2; RBM8A; GSK3B; UPF1; UPF2; DCP2; UPF3B; EXOSC4; XRN1; EXOSC2; EXOSC10; PARN

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

55kDa

Singh, G., (2007) Mol. Cell 27 (5), 780-792

Wet Ice

476

UPF3A

UPF3A

Rabbit

Regulator of nonsense transcripts 3A

NM_023011

QRYHVDDGRRHRAHHEPERLSRRSEDEQRWGKGPGQDRGKKGSQDSGAPG