Upstream-bindeiwit 1 (UBP1) (NM 014517) Humaan recombinant eiwit

Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity) . Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.[UniProtKB/Swiss-Prot Function]

Purified recombinant protein of Human upstream binding protein 1 (LBP-1a) (UBP1), transcript variant 1, Lys47-Thr269, with N-terminal His tag, expressed in E. coli, 50ug

LBP-1a; LBP-1B; LBP1A; LBP1B

7342

Q9NZI7

NM_014517

3p22.3

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Transcription Factors

25.8 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

UBP1

Human

NP_055332

https://www.ncbi.nlm.nih.gov/gene/7342

https://www.uniprot.org/uniprot/Q9NZI7

https://www.ncbi.nlm.nih.gov/nuccore/NM_014517

https://www.ncbi.nlm.nih.gov/nuccore/NP_055332