
URMC-099
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1229582-33-5
C12623-5mg
LRRK2
Autophagy
CN1CCN (CC1) CC2=CC=C (C=C2) C3=CC4=C (NC=C4C5=CC6=C (C=C5) NC=C6) N=C3
C27H27N5
URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM. URMC-099 also inhibits ABL1 with IC50 of 6.8 nM. URMC-099 induces autophagy.
2 years -80 in solvent
Beschrijving
URMC-099 Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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