UROP11 Antilichaam

UROP11 Antibody: Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues; its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity.

319924

B2RUJ5

CAD90042

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Obesity

UROP11 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1406 - Mouse Spleen Tissue Lysate

1 mg/mL

UROP11 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

UROP11 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

Apba1

Amyloid beta (A4) precursor protein binding, family A, member 1

Mus musculus

Verlaeten O, Casery C, Cavagna S, et al. Identification of Urop11, a novel leptin-modulated gene that is upregulated in the hypothalamus of mice with virus-induced obesity. J. Mol. Endocrinol.2007; 38:3-17.

UROP11 Antibody: X11, Mint, Mint1, Lin-10, Urop11, X11alpha, 6430513E09Rik, X11, Amyloid beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Mint-1

ELISA, WB

30348608

Liquid