USP22 Antilichaam - middengebied: Biotine (ARP58353_P050-Biotine)

Ubiquitin specific peptidase 22

USP3L

23326

Q9UPT9

NP_056091

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human USP22

USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.

UBC; AASDHPPT; STAT3; TAF10; TADA2A; ATXN7; MYC; KAT2A; TRRAP; TAF9B; HIST1H2BD; TADA3; SUMO1; NFATC2; SIRT1; ATXN7L3; FUBP1; HIST2H2BE; HIST2H2AC; MRPL44; ATXN7L3B; USP27X; KIF7; KLHL23; ATXN7L2; TADA1; CCDC101; TADA2B; ENY2; SUPT20H; TAF5L; SND1; CNOT10

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

60kDa

Zhang, X.Y., (2008) Mol. Cell 29 (1), 102-111

Wet Ice

525

USP22

USP22

Rabbit

Ubiquitin carboxyl-terminal hydrolase 22

NM_015276

PSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHE