USP5 Mouse Monoclonal Antibody [Kloon ID: LBI2F5]

Ubiquitin (see MIM 191339) -dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]) . [supplied by OMIM]

Carrier-free (BSA/glycerol-free) USP5 mouse monoclonal antibody, clone LBI2F5

ISOT

Homo sapiens ubiquitin specific peptidase 5 (USP5), transcript variant 2, mRNA.

8078

P45974

Unconjugated

WB: 1:200 - 1:1000, IHC 1:50, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protease

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

USP5

https://www.ncbi.nlm.nih.gov/gene/?term=8078

https://www.uniprot.org/uniprot/P45974