UVRAG Polyklonale Antilichaam
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
UVRAG, also known as p63 or DHTX, is a 699 amino acid cytoplasmic protein. UVRAG has been shown to activate the BECN1/PI 3-kinase complex, which promotes autophagy. Autophagy is the degradation of cellular proteins in the lysosomes, and when this pathway is suppressed, cell growth is deregulated. Mutations in the gene encoding UVRAG have been associated with colon cancer, suggesting that UVRAG is also involved in suppressing the proliferation and tumorigenicity of human colon cancer cells. UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells. Ubiquitously expressed, UVRAG is found at highest levels in kidney, lung, liver and brain. UVRAG contains one C2 domain, which is thought to be involved in calcium-dependent phospholipid binding.
DHTX; Disrupted in heterotaxy; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance associated gene protein; UV radiation resistance-associated gene protein; UVRAG; UVRAG_HUMAN.
7405
• Rabbit
501-600/699
UVRAG
• Polyclonal
• IgG
Unconjugated
KLH conjugated synthetic peptide derived from human UVRAG/DHTX
WB, IHC-P, IF (IHC-P)
Purified by Protein A.
1µg/µl
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
7405
Human, Mouse, Rat, Dog, Horse
Beschrijving
UVRAG Polyklonale Antilichaam Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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