V-9302
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1855871-76-9
C13694-5mg
Amino acid transporter
Transmembrane Transporters
CC1=CC (=CC=C1) COC2=CC=CC=C2CN (CCC (C (=O) O) N) CC3=CC=CC=C3OCC4=CC=CC (=C4) C
C34H38N2O4
V-9302 is a competitive small molecule antagonist of transmembrane glutamine flux, that selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) with an IC50 value of 9.6 μM for inhibition of glutamine uptake in HEK-293 cells. V-9302 blocks Sodium-neutral AA transporter 2 (SNAT2, SLC38A2) and the large neutral AA transporter 1 (LAT1, SLC7A5) as observed in 143B osteosarcoma cells, HCC1806 breast cancer cells and Xenopus laevis oocytes. Dilution of PBS may cause a clear aqueous solution to turn into a uniform suspension.
3 years -20°C powder
Beschrijving
V-9302 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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