VAMP2 Antilichaam

The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.

6844

P63027

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VAMP2 (NP_055047.2) .

Unconjugated

Primary Antibodies

Cancer, Neuroscience, Signal Transduction

Affinity purification

22Rv1

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 16kDa

IgG

VAMP2

Mouse brain

Mouse lung

Rat brain

Vesicle-associated membrane protein 2 (synaptobrevin 2)

Homo sapiens

VAMP2, SYB2, Synaptobrevin 2, VAMP-2, Synaptobrevin-2

WB, IHC

Liquid