VAP-1 Recombinant eiwit

VAP-1 is a type II membrane cell adhesion protein belonging to the copper/topaquinone oxidase family. It is primarily expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. VAP-1 can catalyze the oxidative deamination of low molecular weight amines, and plays an important role in the migration of lymphocytes to inflamed tissue. Inhibition of VAP-1 can protect against inflammation related damage to certain injured tissues. Additionally, VAP-1 can function as a significant prognostic marker for certain cancers and cardiovascular diseases. Recombinant VAP-1 is a mixture of monomeric and disulfide linked homodimeric forms of a 737 amino acid polypeptide corresponding to amino acids 27 to 763 of the VAP-1 precursor.

8639

Q16853

NP_001264660.1

Recombinant Proteins

CHO cells

Cancer, Neuroscience, Signal Transduction

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Room Temp

The lyophilized VAP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted VAP-1 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing VAP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Amine oxidase, copper containing 3

Homo sapiens

HPAO, SSAO, VAP1, VAP-1, Membrane primary amine oxidase, Copper amine oxidase

Human

480306390

Lyophilized