VASP (Ab 239) Antilichaam

Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.

7408

P50552

NP_003361.1

Human, Mouse

VASP (Ab-239) antibody was raised against a peptide sequence around aa. 236~240 (K-V-S-K-Q) derived from Human VASP.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

50 kDa

This antibody detects endogenous level of total VASP protein.

Western Blot: 1:500~1:1000

VASP

Vasodilator-stimulated phosphoprotein

Homo sapiens

Wang HG, et al. (2005) euron; 45 (3) : 389-403. Melichar VO, et al. (2004) Proc Natl Acad Sci U S A; 101 (47) : 16671-6. Jensen BO, et al. (2004) Blood; 104 (9) : 2775-82. Zhuang S, et al. (2004) J Biol Chem; 279 (11) : 10397-407. Smolenski A, et al. (1998) J Biol Chem; 273 (32) : 20029-35. Butt E, et al. (1994) J Biol Chem; 269 (20) : 14509-17.

FLK1, VEGFR2

WB

4507869

Liquid