VASP Antilichaam - C-terminalgebied: Biotine (ARP61209 P050-Biotine)

Vasodilator-stimulated phosphoprotein

7408

P50552

NP_003361

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the C terminal region of human VASP

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

ABI3; FGFR1OP; ABI2; SCGB2A2; CEP250; TP53; XIRP1; UBC; FAT1; FOXK1; PPP4R2; PAAF1; PRPF40A; RPP38; PRMT5; POP7; CUL4B; PSMA5; DDB1; APBB1; YWHAQ; NR4A1; YWHAE; DMRTB1; NPM1; VCAM1; SAT1; ITGA4; FN1; AMOT; SF3B2; SF3A3; ATP6V1F; CPNE3; SRSF9; UBE2N; UAP1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 79%; Rat: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

42kDa

Wet Ice

380

VASP

VASP

Rabbit

Vasodilator-stimulated phosphoprotein

NM_003370

SGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVPAQSE