Vav (Phospho Tyr174) Antilichaam

Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation

7409

P15498

NP_005419.2

Human, Mouse, Rat

Vav (Phospho-Tyr174) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 174 (E-I-Y (p) -E-D) derived from Human Vav.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

95 kDa

This antibody detects endogenous level of Vav only when phosphorylated at tyrosine 174.

Western Blot: 1:500~1:1000

VAV1

Vav 1 guanine nucleotide exchange factor

Homo sapiens

Amarasinghe GK, et al. (2005) Biochemistry; 44 (46) : 15257-68. Charvet C, et al. (2005) J Biol Chem; 280 (15) : 15289-99. Miura-Shimura Y, et al. (2003) J Biol Chem; 278 (40) : 38495-504. Kuhne MR, et al. (2000) J Biol Chem; 275 (3) : 2185-90.

VAV, P53, VAV

WB

7108367

Liquid