VAV3 (fosfo Tyr173) Antilichaam

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

10451

Q9UKW4

NP_006104.4

Human, Mouse

VAV3 (phospho Tyr173) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y (p) -E-D) derived from Human VAV3.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

100 kDa

IgG

The antibody detects endogenous levels of VAV3 only when phosphorylated at tyrosine 173.

Western Blot: 1:500~1:1000

VAV3

Vav 3 guanine nucleotide exchange factor

Homo sapiens

Trenkle T., Nucleic Acids Res. 26:3883-3891 (1998) .

Movilla N., Mol. Cell. Biol. 19:7870-7885 (1999) .

VAV3, FLJ40431, Guanine nucleotide exchange factor VAV3

WB

120432044

Liquid