VEGF Receptor 2 Antilichaam

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

3791

P35968

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human VEGF Receptor 2 (NP_002244.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction, Stem Cell

Affinity purification

Mouse heart

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 240kDa

IgG

KDR

Mouse liver

Mouse lung

Kinase insert domain receptor (a type III receptor tyrosine kinase)

Homo sapiens

Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD309, KDR, FLK1, VEGFR2

WB, IHC

Liquid