VEGF121 Aanbevolen eiwit

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant human VEGF121 is a 28.4 kDa disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains.

7422

P15692-9

NP_001028928.1

Recombinant Proteins

E. coli

Cancer, Cell Cycle, Growth Factors, Obesity, Signal Transduction

Room Temp

The lyophilized VEGF121 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted VEGF121 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing VEGF121 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Vascular endothelial growth factor A

Homo sapiens

VPF, VEGF, MVCD1, Vascular endothelial growth factor A, Vascular permeability factor, VEGF-A

Human

76781487

Lyophilized