VEGF165 Aanbevolen eiwit

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF165 is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

7422

P15692-4

NP_001028928.1

Recombinant Proteins

E. coli

Cancer, Cell Cycle, Growth Factors, Obesity, Signal Transduction

Room Temp

The lyophilized VEGF165 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted VEGF165 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing VEGF165 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Vascular endothelial growth factor A

Homo sapiens

VPF, VEGF, MVCD1, Vascular endothelial growth factor A, Vascular permeability factor, VEGF-A

Human

76781487

Lyophilized