VEGFA Antilichaam - C-terminaal gebied: Biotine (ARP60980 P050-Biotine)

VPF, VEGF, MVCD1

7422

P15692-12

Human

The immunogen is a synthetic peptide directed towards the C-terminal region of Human VEGFA

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

ILF3; HNRNPL; NRP1; FLT1; LYVE1; KDR; PRRG4; VPS35; U2AF1; Flt4; ELAVL1; CRYAB; HNRNPD; HGS; UBC; HSP90AA1; HSPA4; YBX3; ADAMTS1; IGFBP7; NRP2; VEGFB; SEMA3F; PGF; EPHB2; TNXB; GPC1; VTN; VEGFA; SPARC; AKT1; YBX1; CTGF; RB1; HIF1A

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

35kDa

Wet Ice

327

VEGFA

VEGFA

Rabbit

ECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSL