VEGFD (NM 004469) Humaan Recombinant eiwit

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]

Purified recombinant protein of Human c-fos induced growth factor (vascular endothelial growth factor D) (FIGF), Phe89-Arg205, with N-terminal His-Trx tag, expressed in E. coli, 50ug

FIGF; VEGF-D

2277

O43915

NM_004469

Xp22.2

E. coli

N-His-Trx

Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma

Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Druggable Genome, Secreted Protein

33.5 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

VEGFD

Human

NP_004460

https://www.ncbi.nlm.nih.gov/gene/2277

https://www.uniprot.org/uniprot/O43915

https://www.ncbi.nlm.nih.gov/nuccore/NM_004469

https://www.ncbi.nlm.nih.gov/nuccore/NP_004460