VEGFR1 (fosfo Tyr1048) Antilichaam

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

2321

P17948

NP_002010.2

Human, Mouse, Rat

VEGFR1 (phospho Tyr1048) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1048 (D-I-Y (p) -K-N) derived from Human VEGFR1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

150 kDa

IgG

The antibody detects endogenous levels of VEGFR1 only when phosphorylated at tyrosine 1048.

FLT1

Fms-related tyrosine kinase 1

Homo sapiens

Shibuya M., Oncogene 5:519-524 (1990) .

Kendall R.L., Proc. Natl. Acad. Sci. U.S.A. 90:10705-10709 (1993) .

The MGC Project Team; Genome Res. 14:2121-2127 (2004) .

VGFR1, FRT, FLT1, FLT

IHC

156104876

Liquid