VEGFR1 (fosfo Tyr1213) Antilichaam

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

2321

P17948

NP_001153392.1

Human, Mouse, Rat

VEGFR1 (phospho Tyr1213) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 1213 (V-R-Y (p) -V-N) derived from Human VEGFR1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

90 kDa

IgG

The antibody detects endogenous level of VEGFR1 only when phosphorylated at tyrosine 1213.

Western Blot: 1:500~1:1000

FLT1

Fms-related tyrosine kinase 1

Homo sapiens

Raghu H, et al. (2012) Mol Oncol 6, 33-47

Ito N, Huang K, Claesson-Welsh L (2001) Cell Signal 13, 849-54

Ito N, Wernstedt C, Engström U, Claesson-Welsh L (1998) J Biol Chem 273, 23410-8

FLT, FLT1, FRT, Flt-1, Fms-like tyrosine kinase 1

WB

143811474

Liquid