VEGFR2 (Ab 1059) Antilichaam

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

3791

P35968

NP_002244.1

Human, Mouse

VEGFR2 (Ab-1059) antibody was raised against a peptide sequence around aa. 1057~1061 (P-D-Y-V-R) derived from Human VEGFR2.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

210, 230 kDa

This antibody detects endogenous levels of total VEGFR2 protein.

Western Blot: 1:1000

KDR

Kinase insert domain receptor (a type III receptor tyrosine kinase)

Homo sapiens

Zeng H, et al. (2001) J Biol Chem. 276 (35) : 32714-32719. Dougher M, et al. (1999) Oncogene. 18 (8) : 1619-1627.

FLK1, CD309, VEGFR, VEGFR2, C1orf215, LAP18, OP18, FLK1, KDR, VGFR2, VGR2, kinase insert domain receptor

WB

11321597

Liquid