VEGFR2 (Ab 1175) Antilichaam

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

3791

P35968

NP_002244.1

Human, Mouse, Rat

VEGFR2 (Ab-1175) antibody was raised against a peptide sequence around aa.1173~1177 (K-D-Y-I-V) derived from Human VEGFR2.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

230 kDa

This antibody detects endogenous level of total VEGFR2 protein.

Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

KDR

Kinase insert domain receptor (a type III receptor tyrosine kinase)

Homo sapiens

Lamalice L, et al. (2004) . Oncogene. 23 (2) : 434-445. Takahashi T, et al. (2001) . EMBO J . 20 (11) : 2768-2778.

FLK1, CD309, VEGFR, VEGFR2, PKD, PKD1, PRKCM, FLK1, KDR, VGFR2, VGR2, kinase insert domain receptor

IHC, IF

11321597

Liquid