VEGFR2 (fosfo Tyr1059) Antilichaam

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

3791

P35968

NP_002244.1

Human, Mouse

VEGFR2 (phospho-Tyr1059) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1059 (P-D-Y (p) -V-R) derived from Human VEGFR2.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

230 kDa

This antibody detects endogenous level of VEGFR2 only when phosphorylated at Tyrosine 1059.

Western Blot: 1:1000

KDR

Kinase insert domain receptor (a type III receptor tyrosine kinase)

Homo sapiens

Zeng H, et al. (2001) J Biol Chem. 276 (35) : 32714-32719. Dougher M, et al. (1999) Oncogene. 18 (8) : 1619-1627.

FLK1, CD309, VEGFR, VEGFR2, AMPK1, FLK1, KDR

WB

11321597

Liquid