Venlafaxine-d10

Venlafaxine-d10 (Wy 45030-d10) is deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT) /norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

940297-16-5

Wy 45030-d10

12352005

Isotope-Labeled Compounds; Serotonin Transporter

Neuronal Signaling; Others

Cancer-programmed cell death

Neurological Disease; Cancer

CN(C)CC(C1=CC=C(C=C1)OC)C2(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C2([2H])[2H])O

C17H17D10NO2

287.46

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;121 (1-2) :70-5.|[3]Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25 (6) :871-80.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B0196S3/

Isotope-Labeled Compounds

No Development Reported