Verlamelin B

Verlamelin B (Compound 147) is effective against plant pathogenic fungal and is a derivative of Verlamelin.Verlamelin B exhibits potent plant protective activity in vivo, particularly against rice blast and barley powdery mildew. Verlamelin B causes morphological changes in fungal cells, such as swelling or expansion. Verlamelin B exhibits weaker antifungal activity in vitro against plant pathogens such as rice blast, Dipolaris zeae, and Botrytis cinerea. Verlamelin B is useful for research on antifungal activities against plant pathogens[1][2].

1619237-95-4

12352209

Fungal

Anti-infection

Infection

O=C1[C@@]2([H])N(C([C@H](NC([C@H](NC(CCC[C@@H](OC([C@@H](NC([C@H](NC([C@@H](N1)CCC(N)=O)=O)CC3=CC=C(C=C3)O)=O)C(C)C)=O)CCCCCCCCC)=O)CO)=O)C)=O)CCC2

C44H69N7O11

872.06

[1]Ishidoh K, et al.. Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp. J Antibiot (Tokyo) . 2014 Jun;67 (6) :459-63.|[2]Zhang L, et al. Secondary metabolites from hypocrealean entomopathogenic fungi: novel bioactive compounds. Nat Prod Rep. 2020 Sep 23;37 (9) :1181-1206.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11343/

Peptides

No Development Reported