Verlamming3 Antilichaam

Paralemmin3 Antibody: Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.

342979

A6NDB9

NP_001138500

Human

Unconjugated

Primary Antibodies

Innate Immunity

Paralemmin3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1219 - MCF7 Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Mouse: (79%)

Paralemmin3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

Paralemmin3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform

PALM3

Cat. No. 17-012 - MCF7 Cell Slide

Paralemmin 3

Homo sapiens

Chen X, Wu X, Zhao Y, et al. A novel binding protein of single immunoglobulin IL-1 receptor-related molecule: Paralemmin-3. Biochem. Biophys. Res. Commun. 2011; 404:1029-33

Wald D, Qin J, Zhao Z, et al. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 2003; 4:920-7.

Paralemmin3 Antibody: Paralemmin-3

ELISA, WB, ICC, IF

222537747

Liquid