Verrucarine A
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A macrocyclic trichothecene mycotoxin from Myrothecium sp. It is a potent and selective inhibitor of the steroid receptor coactivator-3 and selectively down-regulates its expression.1 It is cytotoxic to multiple types of cancer cells at low nM concentrations (IC50=4.9 nM for HepG2 cells) but not toward normal liver cells.1,2 It enhances TNFα-induced3 and TRAIL-induced apoptosis4. It reduces phosphorylation of IREα and inhibits tunicamycin-induced ER stress in FaO rat liver cells.5
Unconjugated
Off-white solid
-20°C
Beschrijving
Verrucarine A Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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