VGLUT1 Antilichaam/Vesiculaire glutamaattransporter 1

VGLUT1 (Vesicular glutamate transporter 1), also called SLC17A7 and BNPI (Brain-specific Na (+) -dependent inorganic phosphate cotransporter) is responsible for packaging glutamate, the most abundant neurotransmitter in the brain, into synaptic vesicles. These vesicles then release glutamate into the synapse, where it binds to receptors on the postsynaptic neuron, triggering a cascade of events that ultimately lead to the transmission of signals. Without VGLUT1, this process would be disrupted, leading to impaired neurotransmission and potentially affecting brain function. Research has shown that abnormalities in VGLUT1 expression are associated with various neurological disorders, including schizophrenia, Alzheimer's disease, and epilepsy.

Immunohistochemistry (FFPE) : 3.75 µg/mL, ELISA (peptide) LOD: 1:32000

Q9P2U7

Human

Amino acids HDQLAGSDDSEMED were used as the immunogen for this VGLUT1 antibody.

IHC-P, ELISA (peptide)

Antigen affinity

Antigen affinity purified

This VGLUT1 antibody is available for research use only.

Aliquot and store the VGLUT1 antibody at -20°C.

0.5 mg/mL in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide

Optimal dilution of the VGLUT1 antibody should be determined by the researcher.

IHC staining of FFPE human adrenal cortex tissue with VGLUT1 antibody at 3.75ug/ml. Required HIER: steamed antigen retrieval with pH6 citrate buffer; AP-staining.