Viomycine (sulfaathydraat)

Viomycin sulfate hydrate is a potent antibiotic against Mycobacteria. Viomycin sulfate hydrate rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis[1][2].

12352005

Antibiotic; Bacterial

Anti-infection

COVID-19-immunoregulation

Infection

O=C(NC[C@@H](C(N[C@H]1CO)=O)NC(C[C@@H](N)CCCN)=O)[C@](NC(/C(NC([C@@H](NC1=O)CO)=O)=C/NC(N)=O)=O)([H])[C@@](NC(N)=N2)([H])C[C@@H]2O.OS(O)(=O)=O.OS(O)(=O)=O.O.[4.5]

C25H43N13O10.2H2SO4.4.5H2O

962.94

[1]FINLAY AC, et al. Viomycin a new antibiotic active against Mycobacteria. Am Rev Tuberc. 1951 Jan;63 (1) :1-3. |[2]Modolell J, Vázquez. The inhibition of ribosomal translocation by viomycin. Eur J Biochem. 1977 Dec;81 (3) :491-7.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-A0155B/

Natural Products

No Development Reported