VISA Antilichaam [8E11]

VISTA Antibody: VISTA/B7-H5/platelet receptor Gi24 is a single-pass type I membrane protein located at the cell surface. It is an immunoregulatory receptor which can inhibit T-cell response and may promote differentiation of embryonic stem cells, by inhibiting the BMP4 signaling pathway. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation.

64115

Q9H7M9

NP_071436

Human

VISTA antibody was raised against the extracellular domain of human VISTA.

8E11

Unconjugated

Primary Antibodies

Immunology

VISTA Antibody is supplied as protein A purified IgG1.

Cat. No. 1331 - Human Lymphoma Tissue Lysate

1 mg/mL

VISTA Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol.

None

Blue Ice

VISTA antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

VSIR

Cat. No. 1306 - Human Spleen Tissue

VISTA molecule

Homo sapiens

Mayya V., et al . Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. 2009, Sci. Signal. 2:RA46-RA46.

Sakr M.A., et al., GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase. 2010, Cancer Sci. 101:2368-2374.

VISTA Antibody: VISTA molecule, VSIR, B7-H5, B7H5, GI24, PP2135, SISP1, DD1alpha, VISTA, C10orf54, chromosome 10 open reading frame 54, PD-1H, V-set immunoregulatory receptor, V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation, Chromosome 10 Open Reading Frame 54

ELISA, IHC-P, ICC, IF, Flow

64115

Liquid