Viscosine

Viscosin is a cyclic lipopeptide compound produced by the Pseudomonas genus. Viscosin exerts its antibacterial effect through two mechanisms: membrane permeabilization and interference with cell wall synthesis. Viscosin shows significant antibacterial activity against various Gram-positive bacteria, but has no inhibitory effect on fungi. Viscosin can be used for the study of bacterial infections[1][2].

27127-62-4

12352005

Bacterial; Endogenous Metabolite

Anti-infection; Metabolic Enzyme/Protease

Infection

N(C([C@H](NC([C@@H](NC(C[C@@H](CCCCCCC)O)=O)CC(C)C)=O)CCC(O)=O)=O)[C@H]1C(=O)N[C@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CO)C(=O)N[C@@]([C@H](CC)C)(C(=O)O[C@@H]1C)[H]

C54H95N9O16

1126.40

[1]Winther AR, et al. Decreased susceptibility to viscosin in Streptococcus pneumoniae. Microbiol Spectr. 2024 Aug 6;12 (8) :e0062424. |[2]Geudens N, et al. Membrane Interactions of Natural Cyclic Lipodepsipeptides of the Viscosin Group. Biochim Biophys Acta Biomembr. 2017 Mar;1859 (3) :331-339.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-180427/

Natural Products

No Development Reported