Visual Arrestin Polyclonal Antibody

Members of the Arrestin/beta-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors, and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Visual Arrestin, also known as Arrestin, retinal S-antigen or S-Arrestin, is a major soluble photoreceptor protein that regulates light-dependent signal transduction through G protein-coupled receptor (rhodopsin) activation. Visual Arrestin is expressed in retinal photoreceptor cells and the pineal gland. Visual Arrestin is the major pathogenic autoantigen in inflammatory eye disease, such as uveoretinitis and Oguchi disease, a rare autosomal recessive form of night blindness.

V-Arrestin; Visual-Arrestin.arrestin; 48 kDa protein; Retinal S-antigen; S-AG; Rod photoreceptor arrestin.

Human, Mouse, Rat

141-240/405

Visual Arrestin

Unconjugated

KLH conjugated synthetic peptide derived from human Visual Arrestin

WB, ELISA, IHC-P, IHC-F, IF, ICC/IF

Purified by Protein A.

1µg/µl

WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:100-500), ICC/IF (ICC/IF=1:100-500)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.