Visugromab (Powder)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Visugromab (CTL-002) (Powder) is a GDF-15 neutralizing IgG4 mAb. Visugromab (Powder) has synergistic anticancer activity with the anti-PD1 antibody Nivolumab and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
2556646-63-8
CLT-002 (Powder)
12352203
PD-1/PD-L1; TGF-beta/Smad
Immunology/Inflammation; Stem Cell/Wnt; TGF-beta/Smad
Cancer
[Visugromab(Powder)]
[1]Necchi A, et al. Neutralizing GDF-15 in muscle-invasive bladder cancer (MIBC) : A neoadjuvant immunotherapy trial of visugromab (CTL-002) in combination with the anti-PD1 antibody nivolumab (NEO-GDFATHER) [J]. 2023.|[2]Melero I, et al. Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours. Nature. 2025 Jan;637 (8048) :1218-1227.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P99100A/
Inhibitory Antibodies
No Development Reported
Beschrijving
Visugromab (CTL-002) (Powder) is a GDF-15 neutralizing IgG4 mAb. Visugromab (Powder) has synergistic anticancer activity with the anti-PD1 antibody Nivolumab an
Specificaties
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Hsa-miR-1258 miRNA Mimic
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Hsa-miR-4258 miRNA Mimic
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5 nmol
Hsa-miR-4258 miRNA Agomir
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5 nmol