Vitexin-2'-O-glucoside

Vitexin-2''-O-glucoside (Flavosativaside) is a potent and selective alpha-glucosidase inhibitor found in hawthorn leaf flavonoids. Vitexin-2''-O-glucoside can reversibly inhibit the α-glucosidase activity on the brush border of the small intestine, and its inhibitory effect is superior to that of the Acarbose. Vitexin-2''-O-glucoside can be used for the research of type 2 diabetes[1].

61360-94-9

Flavosativaside

12352005

Glycosidase

Metabolic Enzyme/Protease

Metabolism-protein/nucleotide metabolism

Metabolic Disease

OC1=CC(O)=C(C(C=C(C2=CC=C(C=C2)O)O3)=O)C3=C1[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO

C27H30O15

594.52

[1]Li H, et al. Screening and structural characterization of α-glucosidase inhibitors from hawthorn leaf flavonoids extract by ultrafiltration LC-DAD-MS n and SORI-CID FTICR MS[J]. Journal of the American Society for Mass Spectrometry, 2009, 20 (8) : 1496-1503.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N17717/

Natural Products

No Development Reported

Glucosidase