Vm24-toxine TFA
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potassium Channel
Membrane transporter/Ion channel
Vm24-toxin (Vaejovis mexicanus peptide 24) TFA is a peptide composed of 36 amino acids, known for effectively and selectively blocking Kv1.3 channels, exhibiting an affinity (Kd) of approximately 3 pM in lymphocytes. It demonstrates over 1500 times greater affinity for Kv1.3 compared to other tested potassium channels. The structure of Vm24-toxin TFA includes a twisted cystine-stabilized α/β motif, comprising a single-turn α-helix and a three-stranded antiparallel β-sheet, stabilized by four disulfide bridges. Additionally, Vm24-toxin TFA can attenuate the response of CD4+ effector memory T cells to T-cell receptor (TCR) stimulation.
Ice Packs
-20°C
Beschrijving
Vm24-toxine TFA Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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