VNN3 Antilichaam

VNN3 Antibody: The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.

55350

Q9NY84

Q9NY84

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

VNN3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

VNN3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

VNN3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

55 kDa

IgG

Multiple isoforms of VNN3 are known to exist.

VNN3

Cat. No. 10-201 - Human Liver Tissue Slide

Vanin 3

Homo sapiens

Granjeaud S, Naquet P and Galland F. An ESTs description of the new Vanin gene family conserved from fly to human. Immunogenetics 1999; 49:964-72.

Jansen PA, Kamsteeg M, Rodijk-Olthuis D, et al. Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines. J. Invest. Dermatol. 2009;129:2167-74.

Nitto T, Inoue T and Node K. Alternative spliced variants in the pantetheinase family of genes expressed in human neutrophils. Gene 2008; 426:57-64.

Martin F, Malergue F, Pitari G, et al. Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes. Immunogenetics 2001; 53:296-306.

VNN3 Antibody: HSA238982, Vascular non-inflammatory molecule 3, Vanin-3

ELISA, WB, IHC-P

88952267

Liquid