Vorsutuzumabmafodotine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Vorsetuzumab mafodotin (SGN-75) is an Auristatin-based anti-CD70 antibody-drug conjugate (ADC) . Vorsetuzumab mafodotin consists of a humanized monoclonal antibody, Vorsetuzumab and an ADC cytotoxin MMAF. Vorsetuzumab mafodotin has antineoplastic activity[1].
1165741-01-4
Anti-Human CD70 Recombinant Antibody; SGN-75
12352203
Antibody-Drug Conjugates (ADCs) ; Microtubule/Tubulin
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Cancer-programmed cell death
Cancer
99.69
10 mM in DMSO
[Vorsetuzumabmafodotin]
(150 kDa)
[1]M C Ryan, et al. Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody-drug conjugate SGN-75. Br J Cancer. 2010 Aug 24;103 (5) :676-84.
Dry Ice
-80°C, protect from light
http://file.medchemexpress.com/batch_PDF/HY-P99334/Vorsetuzumab-mafodotin-SDS-MedChemExpress.pdf
ADC Related
Phase 1
Beschrijving
Vorsetuzumab mafodotin (SGN-75) is an Auristatin-based anti-CD70 antibody-drug conjugate (ADC) . Vorsetuzumab mafodotin consists of a humanized monoclonal antib
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