Voxelotor (Standaard)
Gecertificeerd

Voxelotor (Standaard)

Catalog #: HY-18681R-01
Maat: 5 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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BTW niet inbegrepen
Gratis verzending vanaf €100

Technische Specificaties

Description

Voxelotor (Standard) is the analytical standard of Voxelotor. This product is intended for research and analytical applications. Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment[1].

CAS Number

1446321-46-5

UNSPSC

12352100

Target

Others; Reference Standards

Related Pathways

Others

Field of Research

Cardiovascular Disease

Smiles

OC1=CC=CC(OCC2=C(C3=CC=NN3C(C)C)N=CC=C2)=C1C=O

Molecular Formula

C19H19N3O3

Molecular Weight

337.37

References & Citations

[1]Oksenberg D, et al. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease. Br J Haematol. 2016 Oct;175 (1) :141-53.|[2]Metcalf B, Chuang C, Dufu K, et al. Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. ACS Med Chem Lett. 2017;8 (3) :321-326.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-18681R/

Scientific Category

Reference Standards

Beschrijving

Voxelotor (Standard) is the analytical standard of Voxelotor. This product is intended for research and analytical applications. Voxelotor (GBT 440) is a potent

Specificaties

ProductnaamVoxelotor (Standaard)
Categorie
Beschikbare grootte5 mg
CatalogusnummerHY-18681R-01