VPS37A Antilichaam

This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

137492

Q8NEZ2

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_689628.2) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 44kDa

IgG

VPS37A

HepG2

Mouse liver

Vacuolar protein sorting 37 homolog A (S. cerevisiae)

Homo sapiens

VPS37A, FLJ32642, FLJ42616, HCRP1, PQBP2, SPG53

WB, IHC, IF

Liquid