VRC01LS
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
VRC01LS is a humanized monoclonal antibody inhibitor targeting the CD4-binding site of HIV-1 envelope glycoprotein (Env) . VRC01LS blocks the binding of HIV-1 to host cell CD4 receptor, inhibiting viral entry. VRC01LS is promising for research of HIV-1 infection[1][2].
12352203
HIV; Virus Protease
Anti-infection
COVID-19-anti-virus
Infection
98.78
[VRC01LS]
(145.94 kDa)
[1]Happe M, et al. Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection. JCI Insight. 2025 Feb 24;10 (4) :e181496.|[2]Gaudinski MR, et al. Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults. PLoS Med. 2018 Jan 24;15 (1) :e1002493.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991246/VRC01LS-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 2
Beschrijving
VRC01LS is a humanized monoclonal antibody inhibitor targeting the CD4-binding site of HIV-1 envelope glycoprotein (Env) . VRC01LS blocks the binding of HIV-1 t
Specificaties
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