VS-IP1

VS-IP1 is an interfering peptide that blocks viperin-mediated STAT1 degradation, thereby preventing coxsackievirus B3 (CVB3) -induced acute heart failure (AHF) [1].

12352209

STAT

JAK/STAT Signaling; Stem Cell/Wnt

Neuroscience-Neuromodulation

Cardiovascular Disease

O=C(N1[C@H](CCC1)C(N[C@H](CCCNC(N)=N)C(N[C@H](CCCNC(N)=N)C(N[C@H](CCCNC(N)=N)C(N[C@H](CCC(N)=O)C(N[C@H](CCCNC(N)=N)C(N[C@H](CCCNC(N)=N)C(N[C@H](CCCCN)C(N[C@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H]2N(C([C@H](CC3=CC=CC=C3)NC([C@H](CC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](C(C)C)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC(CNC([C@H](CO)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC4=CC=CC=C4)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H](CCSC)NC([C@H](CCSC)NC([C@H](CC(N)=O)NC([C@H]([C@H](O)C)NC([C@H](C(C)C)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC2

C162H273N57O47S2

3835.38

[1]Yuan Y, et al. Targeting Viperin prevents coxsackievirus B3-induced acute heart failure. Cell Discov. 2025 Apr 8;11 (1) :34.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11041/

Peptides

No Development Reported