
VSLRGDTRG
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2027476-29-3
Integrin, ERK, FAK
MAPK, Cytoskeletal Signaling, Angiogenesis, Tyrosine Kinase/Adaptors
VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the α2β1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in β1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.
[C@@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CO)=O)CC(C)C)=O)(C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=O)CCCNC(=N)N
C38H69N15O14
960.047
Ice Packs
-20°C
Beschrijving
VSLRGDTRG Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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