VSX1 Antilichaam - middengebied: Biotine (ARP39109_P050-Biotine)

Visual system homeobox 1

PPD, KTCN, PPCD, RINX, KTCN1, PPCD1, CAASDS

30813

Q9NZR4

NP_055403

Human

The immunogen is a synthetic peptide directed towards the middle region of human VSX1

VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in VSX1 can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.

Biotin

Polyclonal Antibody

WB

Affinity Purified

VSX1 is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

38kDa

Tang, Y.G., (2008) Cornea 27 (2), 189-192

Wet Ice

356

VSX1

VSX1

Rabbit

Visual system homeobox 1

NM_014588

VSPENGLEDVAIDLSSSARQETKKVHPGAGAQGGSNSTALEGPQPGKVGA