VSX1 Antilichaam - N-terminaal gebied: Biotine (ARP39108_T100-Biotine)

Visual system homeobox 1

PPD, KTCN, PPCD, RINX, KTCN1, PPCD1, CAASDS

30813

Q9NZR4-2

NP_955457

Human, Cow

The immunogen is a synthetic peptide directed towards the N terminal region of human VSX1

VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. Two transcript variants encoding different isoforms have been found for this gene.

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 79%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

25kDa

Valleix, S., et al., (2006) Invest. Ophthalmol. Vis. Sci. 47 (1), 48-54

Wet Ice

239

VSX1

VSX1

Rabbit

Visual system homeobox 1

NM_199425

MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPG