VVD-214
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
3026500-20-6
RO7589831, VVD-133214
Others
Others
C20H21F2N3O4S
VVD-214 (RO7589831, VVD-133214) is a synthetic allosteric inhibitor of WRN helicase. VVD-214 binds irreversibly to cysteine 727 on WRN, suppressing ATP hydrolysis and helicase activity. VVD-214 exhibits potent efficacy in inducing double-stranded DNA breaks, nuclear enlargement, and cellular apoptosis in cancers with high microsatellite instability (MSI) .
Beschrijving
VVD-214 Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.
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