WASP Antilichaam

Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.

7454

P42768

NP_000368.1

Human, Mouse, Rat

WASP antibody was raised against a peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.

Unconjugated

Primary Antibodies

Stem Cell

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

53 kDa

This antibody detects endogenous level of total WASP protein.

Western Blot: 1:500~1:1000

WAS

Wiskott-Aldrich syndrome

Homo sapiens

Kolluri R., Tolias K. F., Carpenter C. L., Rosen F. S., Kirchhausen T. Proc. Natl. Acad. Sci. U. S. A. 93:5615-5618 (1996) Ramesh N., Anton I. M., Hartwig J. H., Geha R. S. Proc. Natl. Acad. Sci. U. S. A. 94:14671-14676 (1997) Cory G. O. C., Cramer R., Blanchoin L., Ridley A. J. Mol. Cell 11:1229-1239 (2003)

THC, IMD2, SCNX, THC1, WASP, THC

WB

4507909

Liquid