WDR92 Antilichaam

WDR92 Antibody: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR92, also known as monad, contains two WD40 repeats is widely expressed in human tissues, especially testis. Overexpression of this protein or its binding partner RNA polymerase II-associated protein 3 (RPAP3) potentiated apoptosis and caspase-3 activation induced by TNF-α and cycloheximide, suggesting that WDR92, together with RPAP3, may function as a novel modulator of apoptosis.

116143

Q96MX6

NP_612467

Human, Mouse

Unconjugated

Primary Antibodies

Apoptosis

WDR92 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1305 - Human Kidney Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

WDR92 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

WDR92 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

WDR92

Cat. No. 11-701 - Human Testis Tissue Slide

WD repeat domain 92

Homo sapiens

Saeki M, Irie Y, Ni L, et al. Monad, a WD40 repeat protein, promotes apoptosis induced by TNF-alpha. Biochem. Biophys. Res. Commun.2006; 342:568-72.

Itsuki Y, Saeki M, Nakahara H, et al. Molecular cloning of novel Monad binding protein containing tetratricorticopeptide repeat domains. FEBS Lett.582:2365-70.

WDR92 Antibody: WD repeat-containing protein 92, WD repeat-containing protein Monad

ELISA, WB, IHC-P, IF

24308444

Liquid